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In vivo xenograft studies showed significant tumor regression after treatment with this degrader, exceeding the results obtained with 5-fluorouracil 86

doi: 10.3390/ijms231911076 75

A positive association between aconitase activity and GSH/GSSG was found in both cerebellum ( P =0.01) and BA22 ( P =0.03) in our combined case and control cohort (correlation coefficients=0.46 and 0.45, respectively)
