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R.SivakamiM.ThilagavathiT.UthrakumarR.KaviyarasuK

By further elucidating the pathogenic mechanism by which hepatic iron accumulation triggers ferroptosis through the c-Myc-Acsl4 regulatory axis, thereby accelerating the progression of metabolic-associated steatohepatitis (MASH), our research team identified a novel iron chelator, FOT1 (FerroTerminator1, formerly known as CN128), through drug screening, which can prevent and treat the onset and progression of MASH disease [117]

The surface area and average pore diameter of H-MnO 2 -PEG were determined to be 360 m 2 g 1 and 3.94 nm, respectively, by BrunauerEmmettTeller (BET) measurement (Fig

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