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The peptides ability to modulate SK channel activity has been linked to its therapeutic effects, as SK channels play a crucial role in neuronal excitability and synaptic plasticity

doi:10.1007/s00213-024-06735-1 Richie JP Jr, Nichenametla S, Neidig W, Calcagnotto A, Haley JS, Schell TD, Muscat JE

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The expression plasmid pCGPx3M in fusion with translation enhancing element sequence for improving the expression level, the hexahistidine tag for purification and factor Xa cleavage site was constructed successfully