melanotic macule on nail Clinical and dermoscopic findings of benign longitudinal melanonychia due to melanocytic activation differ by skin type and predict likelihood of matrix biopsy Pigmented lesion on nail bed:
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ROS act as secondary messengers and play a crucial role in regulating metabolic responses and homeostasis within and outside the mitochondria

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Nicu C, Jackson J, Shahmalak A, Pople J, Ansell D, Paus R
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