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In these ways, mitochondria contribute to various diseases, including tumors, cardiovascular diseases, neurodegenerative diseases, metabolic abnormalities, ocular diseases, liver diseases, and autoimmune diseases, by inducing mitochondrial dysfunction or through regulating oxidative stress, inflammation, and aging
This applies to glucose-metabolizing enzymes (e.g., hexokinase, aldolase, lactate dehydrogenase, phosphofructokinase, and PDH), which increase considerably in activity between the ages of 15 and 30 days (Takagaki, 1974

& Yakel, J

Cerulli LP, Cavallotti CAP
