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Genetic associations with LDL-cholesterol, HDL-cholesterol, and triglycerides were obtained from UK Biobank and a large consortium mainly in Europeans, Global Lipids Genetics Consortium (GLGC) (188,577 participants of European descent and 7898 participants of non-European descent not taking lipid modulating medication [35])
An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity
