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[1] [2] However, longstanding neurological complications, such as peripheral neuropathy or cognitive changes, may require three to six months of consistent treatment before significant improvement occurs, and some damage may be irreversible if treatment is delayed

Alternatively, in vitro culture of constructs 52,90 can promote increased deposition and organization of ECM, further elevating mechanical properties of these scaffolds (Fig

Rare: hypotension, peripheral ischemia, angina
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