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Furthermore, Olfr78 is expressed in renal afferent arterioles, which act as part of the juxtaglomerular apparatus (JGA) and mediate the secretion of renin, which has a key role in the regulation of blood pressure, and the activation of Olfr78 induces the secretion of renin and elevates blood pressure (Pluznick et al., 2013)

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IP3 diffuses through the cytosol and binds to IP3 receptors on the endoplasmic reticulum, triggering the release of stored calcium ions (Ca2+) into the cytoplasm
doi: 10.1038/s41586-018-0023-4 381 WheelerM
