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In vitro cell culture experiments supported these findings by showing increased fatty acid oxidation and upregulated expression of lipid-related genes

These studies suggest that low circulating IGF-I bioactivity and/or abnormalities of IGF-I signaling in elderly subjects, may play an important role in age-related sarcopenia and osteopenia, where the substitutive IGF-I treatment may be a suitable therapeutic strategy, although this apparent IGF-I resistance may dampen this aim

It is noteworthy that alcohol consumption during exercise exacerbates dyslipidemia and oxidative stress, concomitant with the downregulation of hepatocyte IL-6-p47 phox axis-related protein

Ros signaling under metabolic stress: cross-talk between ampk and akt pathway