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Description
Eine effiziente Metallbindung durch alpha-Liponsure ist zwar im Menschen nicht erwiesen unstrittig ist jedoch ihre Fhigkeit, bei chronischer Metallbelastung, metallinduzierte oxidative Schdigungen wirksam abzufangen.

The study result has shown that the expression of various enzymes involved in oxidative phosphorylation and ATP production (SLC25A5, ATP5B, ATP5A1) was decreased with time, indicating a gradual mitochondrial dysfunction that could contribute to the development of DKD (45)
In addition, the enhancement of miR-153-3p expression impeded cellular programmed cell death

Thus, aside from ferroptosis, some specific lipid peroxidation products have been demonstrated that contributes to the progression of various types of RCD (e.g., necroptosis, pyroptosis, apoptosis) [9,10,11,12]
