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Aging 34, 15811588

Copper binding occurs through histidine imidazole nitrogen and N-terminal amino group, forming stable 1:1 complex

Patients assigned to insulin glargine had a baseline mean A1C of 8.1% and were started on a dose of 10 units once daily

The identified peptide fragments carrying modified Cys residues allow the positional mapping of the electrophile susceptible Cys in the parent proteins [8]
