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Description
NAA interacts with the rate-limiting enzyme of pyrimidine nucleotide biosynthesis, which is a trifunctional enzyme encoded by the CAD gene

J Androl 1996;17:530537

The extent of DNA damage is influenced by nanoparticle characteristics (size, coating), but genotoxicity persists across both biogenic and chemically synthesized AgNPs (Patlolla et al., 2015
Park S, Kim C-J, Ha K-C, Baek H-I, Yang H-J, Kim M-J, et al