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doi:10.1111/j.1440-1746.2006.04595.x Chandrasekaran K, Swaminathan K, Chatterjee S, Dey A (2010) Apoptosis in HepG2 cells exposed to high glucose

Antioxidants, particularly those derived from phytobiotics, play a pivotal role in reducing oxidative stress and inflammation, thereby preserving the integrity of the gut barrier and supporting the immune system

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This multimodal activity profile, which acts across multiple cell types and compartments simultaneously, represents a broader mechanistic footprint than single-target agents, although whether this breadth translates into superior clinical outcomes remains unproven