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The primers used in this study are shown in Table S1
The possible mechanism of LF action includes iron-binding dependent manner (upregulation of divalent metal transporter 1 (DMT1) and transferrin receptor (TFR) and downregulation ferroportin 1 (Fpn1)) [117,118] and/or iron-binding independent manner (regulation of the p-Akt/PTEN or the ERK-CREB pathway in HIF-1-dependent manner) [118,119,120]
The biochemistry and physiology of such aldehydes in mammalian systems are discussed in greater detail in a separate web page, although mechanistic aspects of their formation in plants and their reactions with proteins are very similar
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