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Several human tumors, including breast, ovarian, pancreatic, liver, lung, glioblastoma, prostate, melanoma and colorectal cancer often express increased eNOS, nNOS and iNOS, however, tumor-infiltrating immune cells mainly express iNOS [127]
The biological actions of 1,25(OH)2 VD are directly related to the status of VDR in target tissues where translocation of 1,25(OH)2VD/VDR to the nucleus regulates transcription of target genes
[DOI] [PubMed] [Google Scholar] 44.Rizzo A, Santoni M, Mollica V, Logullo F, Rosellini M, Marchetti A, et al
A lack of Vitamin C can lead to serious conditions such as scurvy
