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[DOI] [PubMed] [Google Scholar] Beligni MV, Fath A, Bethke PC, Lamattina L, Jones RL

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In particular, abused drugs produce adaptations in limbic, associative, and sensorimotor cortico-basal ganglia circuits that alter responses to drugs and contribute to inflexible drug taking and seeking behaviors (for review see Gremel and Lovinger, 2016

Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis
