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Furthermore, MSM can regulate the balance between ROS and antioxidant enzymes by controlling other signaling pathways: Janus kinase/signal transducer and activator of transcription [40,41], nuclear factor (erythroid-derived 2)-like 2, and phosphoinositide 3-kinase/protein kinase B [37]

When agents such as DNase or N -acetylcysteine disrupt the mucus layer, goblet cells and submucosal glands begin secreting mucins to rebuild the barrier

The COVID-19 virus utilizes angiotensin-converting enzyme 2 (ACE2) receptor for entry into the cells

However, in zebrafish, PS-NPs affect glucose homeostasis by increasing cortisol secretion and such alternation in cortisol levels causes behavioral changes by interfering with brain cells electrical activity that alters important molecules like neurotransmitters, enzymes, and receptors (171)