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250,251,252 In addition, aging affects the mitochondrial membrane potential and proton gradient across the mitochondrial inner membrane, which is the driving force for ATP synthesis

Roussel AM, Hininger I, Benaraba R, et al

It suppresses appetite and boosts metabolism 3

Lys413 was located near the NADP + -binding pocket, which may affect NADP + binding when it is mutated to a Gln residue (Supplementary Fig
