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This has lead to the use of alternate velocity equations which do not use the kinetic constants kcat and Km at all, instead depending on a different rate constant, (Toppo et al., 2009)

Lack of traceability prevents comparison between experiments and undermines data reliability

Zhang J, Qiao W, Luo Y

Proteogenomic studies have uncovered substantial differences in mitochondrial protein expression between primary and metastatic CRC, particularly in pathways related to energy metabolism, electron transport, and mitochondrial quality control mechanisms [169]
