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The activation of the transcription factors NF-B, c-Jun, and p38 was suppressed after histamine-induced activation of RBL-2H3 cells

Rapid improvement- While the symptoms of b12 deficiency can be debilitating and disruptive to daily life, the injections provide a rapid response, boosting b12 levels instantly, for a quick reduction in the severity of common symptoms, like fatigue, weakness, and cognitive impairments
Nat Rev Endocrinol 8(3):160171
