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Tachyphylaxis Rapid Exhaustion of the Readily Releasable Pool : The primary neurobiological mechanism driving acute stimulant tolerance is the rapid exhaustion of the readily releasable pool (RRP) of synaptic vesicles (Kaeser and Regehr, 2017

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Neuropeptide transmission in brain circuits

Pyridoxine (B6): Supports immune function, formation of red blood cells, protects against inflammatory changes
