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Glutathione is composed of 3 peptides : glutamic acid, cysteine and glycine

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This anti-CCP production and translocation into the systemic circulation has been proposed to accelerate the development of RA with interstitial lung disease for individuals who are genetically predisposed (e.g., gain-of-function MUC5B promoter variant reducing mucociliary function in small airways responsible for clearing inhaled particles in the lungs (170))

The molecular masses of all protein species were monitored by liquid chromatographytime-of-flight mass spectrometry (LC/MS TOF 6230B, Agilent, Santa Clara, CA, USA) using the MassHunter Qualitative Analysis 12.0 software (Agilent, Santa Clara, CA)