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He developed spontaneous acute left-sided facial nerve paralysis

Adults over 50 who often have reduced stomach acid and therefore absorb less B12

Budget-constrained individuals: If cost is a major concern, focus resources on diet, exercise, and possibly oral supplements first
et al., Selective and membrane-permeable small-molecule inhibitors of nicotinamide N-methyltransferase reverse high-fat diet-induced obesity in mice, Biochem Pharmacol, 2018
