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141 SWI/SNF mutations are present in nearly 25% of cancers, which led us to wonder whether other SWI/ SNF-mutated tumors are also sensitive to glutaminase inhibitors

Cureus 15 (8), e43595

Sun Y, Qiao Y, Liu Y, Zhou J, Wang X, Zheng H, et al

3.2 Methionine restriction potentiates oxidative stress by impairing tumor cell antioxidant defenses A state of oxidative stress arises when ROS are produced and eliminated at unequal rates, causing harm to cellular components
