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One-carbon metabolism and schizophrenia: current challenges and future directions
Nonerythropoietic erythropoietin mimetic peptide ARA290 modulates inflammatory responses in experimental models
In a randomized double-blind crossover study, VC (1,000 mg) in combination with dietary nitrates given to untreated hypercholesterolemic subjects for 4 weeks was found to reduce oxidized low-density lipoprotein (oxLDL), triglycerides and inhibit oxidative stress by increasing the total plasma NO metabolites (48)
In this work, GSH-CDs was demonstrated as an effective candidate for delaying disc degeneration, which effectively improves the conditions of malignant oxidative stress within the NPCs microenvironment in a multiple cascade-like activities manner, that is, inhibits the senescence of NPCs induced by excessive accumulated ROS via exerting multiple antioxidant enzyme activity