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To overcome these troubles, we and two other teams identified the causative gene which was called OCTN2 historically, now known as SLC22A5, around the same time in 1999.3-5 The discovery allows making use of a simple DNA mutation test to make a definitive diagnosis

These breakthroughs not only bring new treatment hope to cancer patients but also open innovative pathways for future medical research

As demonstrated, the molecule is expressed in the left ventricle, outer curvature of the right ventricle, and cardiac outflow tract of the developing heart

Sonia Shah et al