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Cochrane Database of Systematic Reviews 2011, Issue 11

Variations in the dynamic levels of these components can result in modifications to the immune response and stromal cell functionality, thereby fostering a microenvironment conducive to tumorigenesis (Table 1)

Brandsma E, Houben T, Fu J, Shiri-Sverdlov R, Hofker M

In particular, the essential amino acids lysine, methionine and threonine, which are responsible for muscle formation or healthy bone structure and connective tissue, are only available to a limited extent in basic feed
