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The widely accepted hypothesis proposes that motor neuron degeneration arises from the interaction between genetic susceptibility and environmental factors, primarily through mitochondrial dysfunction and cytoskeletal disruption mediated by oxidative stress and excitotoxicity (Zhou et al., 2023)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 208.Kwon S.S., Kim S.Y., Kong B.J., Kim K.J., Noh G.Y., Im N.R., Lim J.W., Ha J.H., Kim J., Park S.N

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