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VEGFR2 activation triggers downstream Akt phosphorylation and endothelial nitric oxide synthase signaling, raising nitric oxide output and supporting new vessel formation

Its high electron-donating capacity (high negative redox potential) combined with high intracellular concentration (millimolar levels) generate great reducing power.2 This characteristic underlies its potent antioxidant action and enzyme cofactor properties, and supports a complex thiol-exchange system, which hierarchically regulates cell activity.

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It further proposes a personalized exercise prescription framework based on biomarkers