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The fluorescence signal intensities of ICG gradient from the blood vessel to the deep brain parenchyma tissue of mice treated with BEAGA/ApoE-PDHD were significantly increased, compared with that of mice treated with BEAGA-PDHD or ApoE-PDHD (Supplementary Fig

The term selenoproteins therefore is only used for the latter group, which exert specific (enzymatic or structural) functions for cellular metabolism and homeostasis depending on the highly reactive redox-active properties of Sec in their active sites and not executed by the regular S-containing cysteine residues in proteins

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3i) and rescued the anti-proliferative effects of mitochondrial GSH depletion in SLC25A39/40 double knockout cells (Fig