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In fact, the chemical ability of some metabolites to establish hydrogen bonds (indicated by some descriptors) with other functional groups of biomolecules ( e.g
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Each sample was thereafter incubated with 10 l of acetonitrile and stored at 20 C before analysis was performed on a Beckman HPLC instrument operated with System Gold coupled to diode array UVVIS detector module 168
MTX-induced ER stress occurs predominantly through the PERK/CHOP-10 pathway (Koo et al., 2016) (Figure 1)
