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Description
The cysteinylglycine dipeptide can be cleaved into cysteine and glycine by any of several dipeptidases present on the apical surface of the proximal tubule cells (Hydrolysis of Cysteinylglycine and Its Conjugates section)

It has been reported that SCFAs, chiefly butyrate, possess a neuroprotective effect, they promote anti-inflammatory pathways and enhance mitochondrial function in neuronal cells (123)

(2018) Homocysteine directly interacts and activates the angiotensin II type I receptor to aggravate vascular injury Nat Commun 9, 11 (2018)

Overall, the MD is also applicable to OA patients combined with diabetes
