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Evidence has shown that L-carnitine can promote mitochondrial biogenesis by upregulating peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1), a master regulator of mitochondrial biogenesis [14] and that L-carnitine promotes mitochondrial protein acetylation, a chemical modification that improves mitochondrial function and protects against stressors

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In our experiment, MDA levels increased and levels of the antioxidant SOD decreased in the testis tissue in group B, indicating that the production and removal of oxygen-free radicals in the testis tissue of rats in a simulated high-altitude environment were unbalanced