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It is important to note that this central sensitization seen in diabetes is not a separate pathology to DPN but a consequence of it that eventually augments pain sensation
10.1016/j.bbrc.2009.07.007 202 LetoT
Proper sleep hygiene, which includes maintaining a regular sleep schedule, creating a conducive sleep environment, and minimizing exposure to artificial light at night, is essential for supporting circadian health [113, 114]
Its primary function is to inhibit tyrosinase, an enzyme pivotal for melanin production
