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Each peptide targets distinct pathways: GHK-Cu modulates gene expression and copper-dependent enzymes, BPC-157 interacts with angiogenic and nitric oxide pathways, TB-500 regulates actin dynamics and cell migration, and KPV has been investigated for NF-B modulation and inflammatory cytokine signaling

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Despite the development of GLP-1 monoagonists, new peptides that combine the pharmacology of GLP-1 with other gut peptides increase the efficacy of these agonists while reducing their dose-related gastrointestinal side effects
