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Furthermore, blocking NNMT also increases intracellular SAM (s-adenosylmethionine) levels, which may affect epigenetic regulation and promote energy expenditure and inhibit fat synthesis in adipocytes

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Current testing focuses on military-significant or contingency use products, drugs that have limited commercial use (e.g., nerve agent antidotes), and drugs that are purchased in very large quantities, such as ciprofloxacin and doxycycline