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However, in the context of ferroptosis, selective autophagy pathways such as ferritinophagy (autophagic degradation of ferritin) and lipophagy (degradation of lipid droplets) can paradoxically facilitate ferroptosis by elevating the LIP and releasing PUFAs for peroxidation (146,147)

The consequences of the cardiovascular disease-related reductions in CBF include accelerated reduction in frontal, parietal, and temporal grey matter volumes (Anazodo et al., 2013), greater white matter hyperintensity burden (Moroni et al., 2018), cognitive deficits (Jiang et al., 2023), and increased risk of ADRD (Brain et al., 2023)

Digestion 35 , 199204 (1986)