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This finding underscores the potential therapeutic value of inhibiting the mtROS/HIF-2 signaling pathway and ameliorating the hypoxic microenvironment to attenuate the detrimental effects of CXCL4 in MS and other CXCL4-driven inflammatory disorders

Both the A and B side of the command and control subsystem failed, eliminating the possibility of commanding via a back-up command path

Patients with both TP53 mutations and CK have particularly poor post-HCT outcomes with frequent early relapse

The utility of weight loss medications after bariatric surgery for weight regain or inadequate weight loss: A multi-center study