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Changes in mental status are thought to be caused by the liver failing to detoxify neurotoxic compounds like ammonia

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One double-blind, placebo-controlled RCT by investigated the use of ALC for the treatment of established CIPN (grade 2 or 3, NCI-CTC v3.0) in 240 patients with various solid tumours

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The acyl carnitine is then converted to acyl CoA by the action of carnitine palmitoyltransferase II (CPT II), which leads to -oxidation

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[DOI] [PubMed] [Google Scholar] 127.Waniewski RA, Martin DL

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