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In nature, the chemical form cyanocobalamin does not occur and must therefore be transformed in the body in order to take effect

To safely take Vitamin B12 and folic acid together, patients should: Ask their oncologist before starting any supplements Tell their doctor about all current meds and supplements Stick to the recommended doses By working with their healthcare team, cancer patients can make smart choices about supplements

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Moreover, the conservation of SAM supports proper DNA and histone methylation, allowing favorable expression of genes involved in lipid metabolism and insulin sensitivity