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The shift in alignment causes the joint at the base of the big toe to protrude outward, resulting in a visible bump that often becomes tender and swollen over time

This iron overload deposits in vital organs such as the heart, liver, and endocrine glands, leading to complications including cardiac dysfunction, liver disease, diabetes, and hormonal disturbances

Hence, an understanding of the biological mechanisms and molecular mechanisms is urgently needed to develop new therapeutic strategies for the comprehensive treatment of pancreatic cancer

In other words, OXD/POD-like activity, which generates ROS and thereby inflicts oxidative damage on pathogens or cancer cells, has a beneficial therapeutic impact in the context of antimicrobial and antitumor treatments