b12 test while on injections Vitamin Injections: 8 Dosage and Frequency Guidelines How B12 Deficiency Affects Hashimoto's
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The reduced enzymatic activity increases cellular concentrations of both substrates that NNMT would otherwise consume: S-adenosyl-L-methionine (the universal cellular methyl donor) and nicotinamide (the NAD + salvage precursor)

However, the BfR recommends limiting the daily intake to a maximum of 9 g, i.e

Consult a doctor immediately if your urine is red, black, or dark brown or foamy, says Cleveland Clinic
A valid prescription is required from your doctor prior to B12 administration
