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Figure 1 Figure 2 2 Shared pathological mechanisms underlying tinnitus and neurodegenerative diseases Current evidence supports a multi-stage, multi-pathway hypothesis for tinnitus generation

Its multifaceted approach to protection, from neutralizing free radicals to supporting cellular detoxification, makes it uniquely suited to address the complex challenges posed by modern pollution

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This region corresponds to the essential genes of Hsa21 responsible for the different DS phenotypes (Olson et al., 2004