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In India, the prevalence of type 2 diabetes and hypertension ranks among the highest globally, and cardiovascular diseases (Raghavan et al., 2023) and oral health issues are also of significant concern ( S

The expression level of ET-1 in keratinocytes is increased upon exposure to exogenous insults, and ET-1 promotes the repair of oxidative DNA damage by inhibiting the generation of hydrogen peroxide [61, 62]

This innovative delivery system significantly enhances absorption and stability, ensuring more effective transport into the bloodstream and cells where it can exert its full biological effect