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To lessen As absorption by plants, a variety of mitigation strategies have been proposed which include agronomic practices, plant breeding, genetic manipulation, computer-aided modeling, biochemical techniques, and the altering of human approaches regarding consumption and pollution, and in these ways, increased awareness may be generated

For example, the deletion of tumor suppressor genes, such as PTEN and P53 or the activation of tumor genes, such as c-Myc and Ras, may induce changes in nutrient supply, metabolic enzymes, metabolic requirements and many other metabolic characteristics

Induced pluripotent stem cell (iPSC)-derived human liver organoids (iHLOs) are particularly promising, as they can recapitulate the cellular complexity of the liver, including diverse cell types such as hepatocytes, cholangiocytes, endothelial cells, and occasionally Kupffer cells 11

[DOI] [PubMed] [Google Scholar] 117.Xiao M, Zhong H, Xia L, Tao Y, Yin H