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Inhibition of SystemXc-function can lead to GSH depletion and indirectly affect the ability of GPX4 to catalyze lipid peroxide reduction reactions, resulting in ROS accumulation and triggering ferroptosis (Yang et al., 2016)

Some mothers use glutathione for skin-lightening purposes or to treat specific medical conditions

In particular, they frequently fail to account for age-associated changes, comorbidities, and human-specific pathological features (Vitek et al., 2020)

This review provides the key conceptual foundation for astrocyte neuron metabolic cooperation, including how glial metabolism shapes neuronal activity and circuit function
