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Mitochondrial iron overload: causes and consequences

10.1074/jbc.R112.357194 27 KllL.CanterburyJ

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Although this is consistent and mechanistically validated across different preclinical models, as reviewed in the Preclinical and clinical applications of NAD + -modulating interventions for mitochondrial homeostasis and health benefits section, the correspondence between NAD + changes and mitochondrial or metabolic alterations is more complex in human studies
