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Par-4 drives trafficking and activation of Fas and Fasl to induce prostate cancer cell apoptosis and tumor regression Cancer Res 2001 61 : 72557263 Camandola S, Mattson MP

4.3 Autoimmune hepatitis (AIH) AIH is a progressive and chronic inflammatory liver disease possibly induced by the reciprocity of an inducement and environmental factors in a genetically vulnerable individual, affecting mainly females (Heneghan et al., 2013)

4 Discussion Hypertension affects approximately 31.1% of adults worldwide and is a leading cause of premature death globally (42)

152 Molecular biophysics provides deeper insights into how these geometric variations impact the ACL at the microscopic and molecular levels