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In the presence of deoxyadenosine triphosphate (dATP) and adenosine triphosphate (ATP), Cyt-C is released from mitochondria and bound to Apaf-1 to form a poly-complex, which in turn activated the caspase cascade and thus induced apoptosis [72]

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The silencing of one imprinted allele is often mediated by epigenetic mechanisms, such as DNA methylation

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