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In contrast, other lipid transfer proteins, which lack the conserved cysteine motif, are primarily localized at membrane contact sites, specialized inter-organelle junctions that act as central hubs for lipid trafficking and signaling
For example, the addition of semaglutide at a dose of 0.5 mg or 1 mg per week in patients receiving basal insulin resulted in a 1% and 1.8% decrease in HbA1c, respectively, in SUSTAIN- 5
